HOME > Project > References

日本語English

References of the transduced adipocytes for gene therapy

  1. Kuroda M, Holleboom AG, Stroes E, Asada S, Aoyagi Y, Kamata K, Yamashita S, Ishibashi S, Saito Y, Bujo H. (2014) Lipoprotein subfractions highly associated with renal damage in familial LCAT deficiency Arterioscler Thromb Vasc Biol. 34, 1756-1762.
  2. Naito S, Kamata M, Furuya M, Hayashi M, Kuroda M, Bujo H, Kamata K. (2013) Amelioration of circulating lipoprotein profile and proteinuria in a patient with LCAT deficiency due to a novel mutation (Cys74Tyr) in the lid region of LCAT under a fat-restricted diet and ARB treatment. Atherosclerosis. 228, 193-197.
  3. Fukaya Y, Kuroda M, Aoyagi Y, Asada S, Kubota Y, Okamoto Y, Nakayama T, Saito Y, Satoh K, Bujo H. (2012) Platelet-rich plasma inhibits the apoptosis of highly adipogenic homogeneous preadipocytes in an in vitro culture system. Exp. Mol. Med. 44, 330-339.
  4. Aoyagi Y, Kuroda M, Asada S, Tanaka S, Konno S, Tanio M, Aso M, Okamoto Y, Nakayama T, Saito Y, Bujo H. (2012) Fibrin glue is a candidate scaffold for long-term therapeutic protein expression in spontaneously differentiated adipocytes in vitro. Exp Cell Res. 318, 8-15.
  5. Kuroda M, Bujo H, Aso M, Saito, Y. (2011) Adipocytes as a vehicle for ex vivo gene therapy: Novel replacement therapy for diabetes and other metabolic diseases. J. Diabetes Invest. 2, 333-340.
  6. Asada S, Kuroda M, Aoyagi Y, Fukaya Y, Tanaka S, Konno S, Tanio M, Aso M, Satoh K, Okamoto Y, Nakayama T, Saito Y, Bujo H. (2011) Ceiling culture-derived proliferative adipocytes retain high adipogenic potential suitable for use as a vehicle for gene transduction therapy. Am. J. Physiol. Cell Physiol. 301, C181-C185.
  7. Aoyagi Y, Kuroda M, Asada S, Bujo H, Tanaka S, Konno S, Tanio M, Ishii I, Aso M, Saito Y. (2011) Fibrin glue increases the cell survival and the transduced gene product secretion of the ceiling culture-derived adipocytes transplanted in mice. Exp. Mol. Med. 43, 161-167.
  8. Kuroda M, Aoyagi Y, Asada S, Bujo H, Tanaka S, Konno S, Tanio M, Ishii I, Machida K, Matsumoto F, Satoh K, Aso M, Saito Y. (2011) Ceiling culture-derived proliferative adipocytes are a possible delivery vehicle in enzyme replacement therapy in lecithin:cholesterol acyltransferase deficiency. Open Gene Ther. J. 4, 1-10.
  9. Asada S, Kuroda M, Aoyagi Y, Bujo H, Tanaka S, Konno S, Tanio M, Ishii I, Aso M, Saito Y. (2011) Disturbed apolipoprotein A-I-containing lipoproteins in fish-eye disease are improved by the lecithin:cholesterol acyltransferase produced by gene-transduced adipocytes in vitro. Mol. Genet. Metab. 102, 229-231.
  10. Ito M, Bujo H, Takahashi K, Arai T, Tanaka I, Saito Y. (2005) Implantation of primary cultured adipocytes that secrete insulin modifies blood glucose levels in diabetic mice. Diabetologia. 48, 1614-1620.
お問合せ 研究員・技術開発員 募集